Acetylcysteine or Airbron
Acetylcysteine is a derivative of a naturally occurring amino acid, 1-cysteine. It reduces viscosity of sputum in vitro.
The drug is rapidly metabolized in the body. Also called as Mesna.
There are many uses of acetylcycteine in medical practice. The most inportant being as a mucolytic.
Clinically, 2ml. of 10% Acetylcysteine solution are nebulized into a face mask every 8 hours for 5-10 days to liquefy viscous tracheobronchial secretions.
It can also be administered by direct instillation into the tracheobronchial tree through a tracheostomy, a bronchoscope or a percutaneous intratracheal catheter, or as an aerosol.
The following are the different uses:
- As mucolytic
- For renal protection while administering contrast for doing radiological examinations like Ct scan and MRI with a radioactive material called contrast. Administering it before injecting the contrast helps in protecting the kidneys and the body from the harmful and damaging effect of the radioactive contrast material. This use as prevention of radiocontrast induced nephropathy.
- In Hemorrhagic cystitis
- In treatment of obstructive lung disease
- Paracetamol Over dosage treatment
- Treating psychiatric diseases like Depression, bipolar disorder, OCD, schizophrenia, Alzheimer’s disease
Acetylcysteine side effects
Adverse reactions effects include bronchospasm, fever, nausea, vomiting, stomatitis, rhinorrhea and hemoptysis. It reacts with most metals and with rubber.
Carbocysteine and methylcysteine (Visclair) have similar properties as this medicine.